Non-Invasive Prenatal Test (NIPT) is the most sensitive Screening test for Aneuploidy (ie. having an abnormal number of chromosomes eg. Downs Syndrome, Turners Syndrome, etc). NIPS can be done as early as 10 weeks in pregnancy and is not dependant on Ultrasonography findings. It is operator independant. Unlike Dual / Triple / Quadruple / Penta Marker which relies on measuring hormonal levels in mother's blood this test is performed by extracting Cell free Fetal DNA (cffDNA) circulating in mother's blood. Hence it's accuracy is higher.
Newborn Screening (NBS) is a very useful First
Test for the baby. It looks out for several common
disorders which are otherwise undetactable
HOW DOES DUO work?
DUO consists of two
tests, one for the pregnant mother and one for the
baby. Mother's blood will be collected in a special
tube. The blood will be processed to extract cffDNA.
The process takes about 8-10days. Digital report
will be available by day 10 of sample reaching the
lab. Alongwith the Normal NIPT report you will be
handed with a Guthrie card kit. The kit contains a
Guthrie card (manufactured as per CLSI guidelines),
Auto Lancet (as per WHO guidelines) and seld
addressed envelope. This NBS Kit has to be handed
over to your baby's doctor after it is born. Baby's
doctor will collect a few drops of blood from the
baby's heel (Heel-prick) on the Guthrie card. This card is to be
dried (DBS) in ambient room temperature (away from
sunlight). Fill the form attached to the card. Once
dried you need to ship it to us on the address
printed on the envelope.
The specialised NBS lab will process the sample ie. Dried Blood Spot (DBS) and email you the report.
NIPS samples are sent to SN Gene Lab, Surat whereas NBS samples are sent to NeoGen Labs, Bengaluru