DUO

Non-Invasive Prenatal Test (NIPT) is the most sensitive Screening test for Aneuploidy (ie. having an abnormal number of chromosomes eg. Downs Syndrome, Turners Syndrome, etc). NIPS can be done as early as 10 weeks in pregnancy and is not dependant on Ultrasonography findings. It is operator independant. Unlike Dual / Triple / Quadruple / Penta Marker which relies on measuring hormonal levels in mother's blood this test is performed by extracting Cell free Fetal DNA (cffDNA) circulating in mother's blood. Hence it's accuracy is higher.

Newborn Screening (NBS) is a very useful First Test for the baby. It looks out for several common disorders which are otherwise undetactable clinically.
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HOW DOES DUO work?

DUO consists of two tests, one for the pregnant mother and one for the baby. Mother's blood will be collected in a special tube. The blood will be processed to extract cffDNA. The process takes about 8-10days. Digital report will be available by day 10 of sample reaching the lab. Alongwith the Normal NIPT report you will be handed with a Guthrie card kit. The kit contains a Guthrie card (manufactured as per CLSI guidelines), Auto Lancet (as per WHO guidelines) and seld addressed envelope. This NBS Kit has to be handed over to your baby's doctor after it is born. Baby's doctor will collect a few drops of blood from the baby's heel (Heel-prick) on the Guthrie card. This card is to be dried (DBS) in ambient room temperature (away from sunlight). Fill the form attached to the card. Once dried you need to ship it to us on the address printed on the envelope.
The specialised NBS lab will process the sample ie. Dried Blood Spot (DBS) and email you the report.